HISTO

PATHOLOGY

GENE EXPRESSION

FLOW

CYTOMETRY

CYTOKINE PROFILING

HIGH CONTENT IMAGING

KINETIC ASSAYS

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HISTOPATHOLOGY

Morphological assessment of mechanistic response of drug to assess proliferation, cell death and immune cell infiltration induced by treatment

 

GENE EXPRESSION

Measurement of differential gene expression across treatment arms in tumor, stromal and immune compartments using NanoString

 

Pan cancer and immune panels for comprehensive analysis of gene signatures and cell scores indicative of drug response

 
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Farcast proprietary images, generated with human tumor tissues

Live 

Dead

HIGH CONTENT IMAGING

Comprehensive evaluation of live-dead cells and immune cells in a Tumor immune MicroEnvironment

 

Quantitative live cell imaging for objective assessment of tumoricidal and immune response to drug modulation

 

FLOWCYTOMETRY

Precise measurement and characterization of diverse immune cell populations within the explant system

 

Customized gating strategies for assessment of specific immune cell type activity indicative of drug response

 

CYTOKINE PROFILING

Multiplexed quantitative evaluation of cytokines/ chemokine release using Luminex.

 

Immune effector cells early response in tumor explants in response to drug exposure.

 
 
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KINETIC ASSAYS

Discrete time course measurements to understand metabolic state and viability of explants in the culture system

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